I have a KLR650 that I enjoy very much:
I bought it and then I lowered my TW200 for my wife to ride. But I found that
I didn't enjoy riding it at the slower pace that she likes on the TW.
So I bought another TW200 for me, and I think that's great.
Much more comfortable riding with similar gearing and power.
Not to say it wouldn't work, but I think it will depend on the rider as well. I used to ride my TW200 with friends on KLRs and I could keep up fine (not on the highway, but otherwise) but I would be riding far more aggresively than the Mrs. is ever going to do.