I've done several sections in my 4x4 and camped along the way.
Things to keep in mind: earlier in the year there is more chance of mud and wet terrain. Some of the route is spots slicker than snake sh*t right off cliff edges. Later in the summer wildfires can shut down some of the route.
The only truly difficult section via motorbike is section 2 and what has been dubbed "baby head hill" due to the baby head sized rock garden you must traverse.
On a tdub I'd suggest rotopax or spare fuel.
Wish I had the setup to moto camp, I'd be all over this.